Create a 60-90 second animated video to illustrate the innovative design of an allosteric DNA nanorobot for targeted glioma therapy, based on a study published in Science Robotics. Start with a dynamic scene showing the challenge: malignant gliomas, aggressive brain tumors, are hard to treat because the blood-brain barrier (BBB) blocks drugs like doxorubicin (Dox). Introduce the solution: a compact tetrahedral DNA nanorobot (~10 nm), built using DNA origami. Emphasize its key feature: an allosteric, pH-responsive mechanism driven by cytosine protonation, triggering structural changes in the acidic tumor microenvironment (pH 6.5–6.8). Depict the nanorobot smoothly crossing the BBB, guided by AS1411 aptamers targeting nucleolin on glioma cells. Show a vibrant animation of the nanorobot releasing Dox at the tumor site as a glowing burst, driven by pH-induced conformational shifts, leading to tumor suppression. Use clear visuals, such as a 3D tetrahedral nanorobot navigating a stylized brain environment, with glowing effects to highlight pH responsiveness and drug release. Include simple text overlays (e.g., “pH-Triggered Release” or “BBB Crossing”) and smooth transitions. Maintain a professional yet accessible tone, suitable for researchers, students, and general audiences. Conclude with an inspiring text: “Revolutionizing brain tumor therapy with DNA nanorobots!” Ensure scientific accuracy, vivid colors, and engaging motion to captivate viewers.