NAD, or Nicotinamide Adenine Dinucleotide, is a crucial coenzyme present in every living cell of our body. This remarkable molecule serves as a fundamental building block for cellular energy production, DNA repair mechanisms, and vital cell signaling processes that keep our bodies functioning optimally.
NAD plays a critical role in energy production within our cells. It acts as an electron carrier in the process that converts nutrients into ATP, the universal energy currency of cells. This process primarily occurs in the mitochondria, where NAD helps transform glucose and other nutrients into usable energy that powers all cellular activities.
NAD is crucial for DNA repair and cellular maintenance. It activates PARP enzymes, which are essential for detecting and repairing DNA damage. When DNA is damaged by environmental factors or normal cellular processes, NAD-dependent repair mechanisms spring into action to maintain genomic stability and prevent harmful mutations that could lead to cellular dysfunction.
NAD activates a family of longevity proteins called sirtuins, specifically SIRT1 through SIRT7. These proteins act as cellular guardians, regulating gene expression and promoting cellular health. When NAD levels are sufficient, sirtuins become active and help extend cellular lifespan, improve stress resistance, and maintain optimal cellular function throughout the aging process.
NAD levels naturally decline with age, dropping significantly from our twenties onward. This decline affects multiple organ systems including the brain, heart, muscles, and liver. However, maintaining adequate NAD levels through supplementation or lifestyle interventions can support enhanced energy metabolism, improved brain function, better muscle performance, stronger immune response, and overall healthy aging processes.