Tablet coating is a pharmaceutical manufacturing process where a protective layer is applied to the surface of a tablet. This process aims to improve various tablet characteristics, such as taste, stability, and appearance. Different coating methods are employed, including sugar coating, film coating, and enteric coating, each serving specific

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Tablet coating is a fundamental pharmaceutical manufacturing process where protective layers are applied to tablet surfaces. This process significantly improves tablet characteristics including taste masking, stability enhancement, better appearance, controlled drug release, and protection from environmental factors like moisture and light. Sugar coating is the traditional pharmaceutical coating method that applies multiple layers of sugar-based solutions. The process involves five key steps: sealing coat application, sub-coating with powder, multiple syrup coating layers, coloring and flavoring, and final polishing. This method provides excellent taste masking, attractive appearance, and good protection, though it requires more time and materials compared to modern alternatives. Film coating is a modern pharmaceutical coating method that applies thin polymer films to tablets using spray technology. This single-step process uses polymer-based solutions sprayed onto tablets with controlled film thickness. Film coating offers significant advantages including faster processing, precise control, lower weight gain, better uniformity, and cost-effectiveness compared to traditional sugar coating methods. Enteric coating is a specialized pharmaceutical coating method that uses acid-resistant polymers. These coatings are designed to resist dissolution in stomach acid with pH one to three, but dissolve readily in the alkaline environment of the intestines with pH six to eight. This mechanism protects acid-sensitive drugs and enables targeted drug delivery. Enteric coating is commonly used for aspirin, probiotics, enzymes, and anti-inflammatory drugs. To summarize what we have learned about tablet coating: This pharmaceutical process significantly enhances drug stability, appearance, and patient compliance. Sugar coating provides excellent taste masking but requires longer processing time. Film coating offers faster and more efficient processing with precise control. Enteric coating enables targeted drug delivery and protects acid-sensitive medications. Each coating method serves specific pharmaceutical applications and requirements, making tablet coating an essential part of modern pharmaceutical manufacturing.